Buy 4-ANPP Cas 21409-26-7

Buy 4-ANPP Cas 21409-26-7

21409-26-7

• 

• Basic information

  1. Product Name: 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE
  2. Synonyms: N-PHENYL-1-(2-PHENYLETHYL) PIPERIDIN-4-AMINE;(1-PHENETHYL-PIPERIDIN-4-YL)-PHENYL-AMINE;N-Phenyl-1-(2-phenethyl)piperidin-4-amine;N-(1-PHENETHYL-PIPERIDIN-4-YL)-ANILINE;N-[1-(2-Phenylethyl)-4-piperidinyl]benzenamine;N-Phenyl-1-(2-phenylethyl)-4-piperidinamine;4-Piperidinamine, N-phenyl-1-(2-phenylethyl)-;N-Phenyl-N’-[1-(2-phenylethyl)]-4-piperidine Discontinued See: A625875
  3. CAS NO:21409-26-7
  4. Molecular Formula: C₁₉H₂₄N₂
  5. Molecular Weight: 280.40726
  6. EINECS: N/A
  7. Product Categories: Aromatics;Metabolite & Impurities;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
  8. Mol File: 21409-26-7.mol

• Chemical Properties

  1. Melting Point: 94-96°C
  2. Boiling Point: 424.604 °C at 760 mmHg
  3. Flash Point: 161.923 °C
  4. Appearance: Pale yellow solid
  5. Density: 1.075 g/cm³
  6. Vapor Pressure: 2.04E-07mmHg at 25°C
  7. Refractive Index: 1.603
  8. Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
  9. Solubility: N/A
  10. PKA: 9.03±0.10(Predicted)
  11. CAS DataBase Reference: 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE(CAS DataBase Reference)
  12. NIST Chemistry Reference: 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE(21409-26-7)
  13. EPA Substance Registry System: 4-AMINOPHENYL-1-PHENETHYLPIPERIDINE(21409-26-7)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: 22-36/37/38
  3. Safety Statements: 22-37/39-46
  4. RIDADR: UN1230 – class 3 – PG 2 – Methanol, solution
  5. WGK Germany: 2
  6. RTECS:
  7. HazardClass: N/A
  8. PackingGroup: N/A
  9. Hazardous Substances Data: 21409-26-7(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

21409-26-7 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn’t provide relevant sales information.

21409-26-7 Usage

Uses

Used in Pharmaceutical Synthesis:
4-AMINOPHENYL-1-PHENETHYLPIPERIDINE is used as a chemical intermediate for the synthesis of fentanyl and related opioids. It plays a crucial role in the production of potent analgesic medications used in medical settings for pain management.
Used in Research Applications:
4-AMINOPHENYL-1-PHENETHYLPIPERIDINE is used as an analytical reference material for research purposes. It aids scientists in understanding the chemical properties and metabolic pathways of opioids, contributing to the development of new drugs and therapies.
Used in Forensic Applications:
4-AMINOPHENYL-1-PHENETHYLPIPERIDINE is utilized as a certified reference material in forensic analysis. It helps in the identification and quantification of opioids in criminal investigations, particularly in cases involving illicit drug trade and substance abuse.
Used in Metabolite Studies:
4-AMINOPHENYL-1-PHENETHYLPIPERIDINE is used as a metabolite of acetyl fentanyl, butyryl fentanyl, furanyl fentanyl, acrylfentanyl, and fentanyl. Studying its presence and behavior in biological systems can provide insights into the metabolism and potential toxic effects of these opioids.

Check Digit Verification of cas no

The CAS Registry Mumber 21409-26-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,0 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21409-26:
(7*2)+(6*1)+(5*4)+(4*0)+(3*9)+(2*2)+(1*6)=77
77 % 10 = 7
So 21409-26-7 is a valid CAS Registry Number.

InChI:InChI=1/C19H24N2/c1-3-7-17(8-4-1)11-14-21-15-12-19(13-16-21)20-18-9-5-2-6-10-18/h1-10,19-20H,11-16H2

21409-26-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-Aminophenyl-1-phenethylpiperidine

1.2 Other means of identification

Product number	–
Other names	N-phenyl-1-(2-phenylethyl)piperidin-4-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier’s details

1.5 Emergency phone number

Emergency phone number

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Service hours

Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21409-26-7 SDS

21409-26-7Upstream product

• 39742-60-41-(2-phenylethyl)-4-piperidinone 
• 62-53-3aniline 
• 23056-29-3phenyl-piperidin-4-yl-amine 
• 103-63-91-phenyl-2-bromoethane 
• 64-04-0phenethylamine 
• 57958-48-2N-(1-phenethylpiperidin-4-ylidene)aniline 
• 122-78-1phenylacetaldehyde 
• 41979-39-94-piperidone hydrochloride 

21409-26-7Downstream Products

• 3258-84-2N-<1-(2-Phenylethyl)-4-piperidyl>-N-phenylacetamide 
• 82003-73-42-chloro-N-phenyl-N-<1-(2-phenylethyl)-4-piperidinyl>acetamide 
• 437-38-7N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide 
• 52994-23-7Carboxyfentanyl 
• 1184873-14-0N-[1-(2-phenylethyl)-piperidin-4-yl]-nitrosoaniline 
• 526191-19-55-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid 
• 1277097-11-62-(2-oxo-2-((1-phenethylpiperidin-4-yl)(phenyl)amino)ethoxy)acetic acid 
• 1338727-47-1tryptophan 3,5-bis(trifluoromethyl)benzyl ester 4-oxo-4-((1-phenethylpiperidin-4-yl)(phenyl)amino)butanoate 
• 1338727-48-2tryptophan 3,5-bis(trifluoromethyl)benzyl ester 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoate 
• 1338727-49-3tryptophan 3,5-bis(trifluoromethyl)benzyl ester 2-(2-oxo-2-((1-phenethylpiperidin-4-yl)(phenyl)amino)ethoxy)acetate 
• 1338727-32-4C₂₃H₂₇N₂O₂⁽¹⁺⁾*ClHO₄*ClO₄^(1-)
• 1338727-35-7C₂₄H₂₉N₂O₂⁽¹⁺⁾*ClHO₄*ClO₄^(1-)
• 1338727-38-0C₂₃H₂₇N₂O₃⁽¹⁺⁾*ClHO₄*ClO₄^(1-)
• 1338727-40-43,5-bis(trifluoromethyl)benzyl 3-(1H-indol-3-yl)-2-(4-oxo-4-((1-phenethylpiperidin-4-yl)(phenyl)amino)butanamido)propanoate 

21409-26-7Relevant academic research and scientific papers

4-ANPP, also known as 4-anilino-N-phenethylpiperidine (4-ANPP), 4-aminophenyl-1-phenethylpiperidine, or despropionyl fentanyl,^[3] is a direct precursor to fentanyl and acetylfentanyl. It is commonly found as a contaminant in samples of drugs containing fentanyl, which may include samples represented by the supplier as heroin or other opioids.^[4] It is not psychoactive and is present only as a result of improper chemical purification.

4-ANPP is useful in the synthesis of pharmaceuticals, primarily fentanyl and related analogs. Paul Janssen (founder of Janssen Pharmaceutica) first synthesized fentanyl in 1960 using a similar method, with Benzylfentanyl as an intermediate.^[5] The following synthesis, developed by an individual under the pseudonym of Siegfried, involves the reductive amination of N–phenethyl-4-piperidinone (NPP) with aniline to make to 4-ANPP. This product is reacted with propionyl chloride or acetyl chloride to form either fentanyl or acetylfentanyl.

• 1-Boc-4-AP