Buy Levomethamphetamine Cas 33817-09-3

Buy Levomethamphetamine Cas 33817-09-3

Levomethamphetamine^[a] (INN: levmetamfetamine) is an optical isomer of methamphetamine primarily used as a topical nasal decongestant.^[2] Levomethamphetamine is used to treat nasal congestion from allergies and the common cold.^[7] It was first used medically as decongestant beginning in 1958 and has been used for such purposes, primarily in the United States, since then.^[8]

Levomethamphetamine is significantly less potent in terms of physiologic and subjective drug effects than racemic methamphetamine, dextromethamphetamine, and related amphetamines, especially when used as a nasal decongestant at therapeutic doses.

Levomethamphetamine is used to treat nasal congestion related to the common cold and allergic rhinitis. It is available in the form of an inhaler containing 50 mg total per inhaler and delivering between 0.04 and 0.15 mg of the drug per inhalation.^[2] Inhalers with a total of 113 mg levomethamphetamine were previously marketed in the United States, but the total amount was eventually reduced to 50 mg. Buy Levomethamphetamine Cas 33817-09-3

When the nasal decongestant is taken in excess, levomethamphetamine has potential side effects. These would be similar to those of other decongestants. Buy Levomethamphetamine Cas 33817-09-3

Levomethamphetamine acts as a selective norepinephrine releasing agent.^{[12][16][18][4]} The potencies of levomethamphetamine, levoamphetamine, dextromethamphetamine, and dextroamphetamine in terms of norepinephrine release in vitro and in vivo in rats are all similar.

Conversely, whereas dextromethamphetamine and dextroamphetamine are relatively balanced releasers of dopamine and norepinephrine in vitro, levomethamphetamine is about 15- to 20-fold less potent in inducing dopamine release relative to norepinephrine release.^{[16][18][4][12][21]} Moreover, whereas levoamphetamine is about 3- to 5-fold less potent in terms of dopamine release than dextroamphetamine in vivo, levomethamphetamine is dramatically less potent than dextromethamphetamine and substantially less potent than Buy Levomethamphetamine Cas 33817-09-3 levoamphetamine in this regard.^[20][19][22]

In accordance with the findings of catecholamine release studies, levomethamphetamine is 2- to 10-fold or more less potent than dextromethamphetamine in terms of psychostimulant-like effects in rodents.^[23][24][25] For comparison, levoamphetamine is only 1- to 4-fold less potent than dextroamphetamine in its stimulating and reinforcing effects in monkeys and humans.^[19][26]

The effects of levomethamphetamine are qualitatively distinct relative to those of racemic methamphetamine and dextromethamphetamine and it does not possess the same potential for euphoria or addiction that these drugs possess.^{[2][25][27][4][22]} In clinical studies, levomethamphetamine at oral doses of 1 to 10 mg has been found not to affect subjective drug responses, heart rate, blood pressure, core temperature, electrocardiography, respiration

33817-09-3

• 

• Basic information

  1. Product Name: (-)-2-[METHYLAMINO]-1-PHENYLPROPANE
  2. Synonyms: R(-)-METHAMPHETAMINE;(-)-DEOXYEPHEDRINE;LEVO-METHAMPHETAMINE;(-)-METHAMPHETAMINE;L-METHAMPHETAMINE;METHYL-((R)-1-METHYL-2-PHENYL-ETHYL)-AMINE;(-)-2-[METHYLAMINO]-1-PHENYLPROPANE;(-)-(R)-N,alpha-Dimethylphenethylamine
  3. CAS NO:33817-09-3
  4. Molecular Formula: C₁₀H₁₅N
  5. Molecular Weight: 149.23
  6. EINECS: 251-687-0
  7. Product Categories: N/A
  8. Mol File: 33817-09-3.mol

• Chemical Properties

  1. Melting Point: 38-40 °C
  2. Boiling Point: 215.533 °C at 760 mmHg
  3. Flash Point: 9℃
  4. Appearance: /
  5. Density: 0.907 g/cm³
  6. Vapor Pressure: 0.147mmHg at 25°C
  7. Refractive Index: 1.503
  8. Storage Temp.: 2-8°C
  9. Solubility: N/A
  10. PKA: pKa 9.99(H2O,t =25±0.5,I=0.01)(Approximate)
  11. CAS DataBase Reference: (-)-2-[METHYLAMINO]-1-PHENYLPROPANE(CAS DataBase Reference)
  12. NIST Chemistry Reference: (-)-2-[METHYLAMINO]-1-PHENYLPROPANE(33817-09-3)
  13. EPA Substance Registry System: (-)-2-[METHYLAMINO]-1-PHENYLPROPANE(33817-09-3)

• Safety Data

  1. Hazard Codes: T,F
  2. Statements: 23/24/25-63-36-39/23/24/25-11
  3. Safety Statements: 23-36/37/39-45-36/37-26-16-22
  4. RIDADR: UN 2810 6.1/PG 3
  5. WGK Germany: 3
  6. RTECS: SH4905000
  7. HazardClass: N/A
  8. PackingGroup: N/A
  9. Hazardous Substances Data: 33817-09-3(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3
• Buy Levomethamphetamine Cas 33817-09-3

33817-09-3 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn’t provide relevant sales information.

33817-09-3 Usage

Uses

Used in Pharmaceutical Industry:
(-)-2-[METHYLAMINO]-1-PHENYLPROPANE is used as an active ingredient for its vasoconstrictive properties, primarily in the formulation of over-the-counter nasal decongestants. Its ability to constrict blood vessels helps alleviate nasal congestion and improve breathing.
Used in Forensic Analysis:
(-)-2-[METHYLAMINO]-1-PHENYLPROPANE is used as a starting material in calibrators or controls for various LC/MS or GC/MS applications, such as forensic analysis. Its presence in nasal decongestants and potential for abuse makes it a relevant compound for detecting and analyzing in criminal investigations.
Used in Sports Testing:
As a component of performance-enhancing drugs, (-)-2-[METHYLAMINO]-1-PHENYLPROPANE is used in sports testing to detect and prevent the use of banned substances among athletes. Its presence in samples can indicate the use of prohibited stimulants, ensuring fair competition and adherence to anti-doping regulations.
Used in Clinical Toxicology:
(-)-2-[METHYLAMINO]-1-PHENYLPROPANE is used as a reference compound in clinical toxicology to identify and quantify the presence of amphetamines and related substances in biological samples. This helps in diagnosing cases of drug overdose, intoxication, or substance abuse.
Used in Urine Drug Testing:
In the context of urine drug testing, (-)-2-[METHYLAMINO]-1-PHENYLPROPANE is used as a target analyte for detecting the use of amphetamines and related substances. Its detection in urine samples can indicate recent use of these drugs, aiding in the assessment of drug abuse and the development of appropriate treatment plans.

Synthesis Reference(s)

The Journal of Organic Chemistry, 37, p. 2208, 1972 DOI: 10.1021/jo00978a034

Check Digit Verification of cas no

The CAS Registry Mumber 33817-09-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,1 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33817-09:
(7*3)+(6*3)+(5*8)+(4*1)+(3*7)+(2*0)+(1*9)=113
113 % 10 = 3
So 33817-09-3 is a valid CAS Registry Number.

InChI:InChI=1/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m1/s1

33817-09-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) – Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	Levomethamphetamine

1.2 Other means of identification

Product number	–
Other names	l-Methylamphetamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier’s details

1.5 Emergency phone number

Emergency phone number	–
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33817-09-3 SDS

33817-09-3Upstream product

• 7632-10-2methamphetamin 
• 167421-83-2tert-butyl N-[(1R)-1-methyl-2-phenylethyl]carbamate 
• 141403-49-8(2S)-2-[N-(tert-butoxycarbonyl)amino]-3-phenyl-O-(4-methylphenylsulfonyl)propan-1-ol 
• 122-78-1phenylacetaldehyde 
• 4436-24-21,2-epoxy-3-phenylpropane 
• 74-89-5methylamine 
• 171337-01-2(R)-N-methyl-N-(1-methyl-2-oxo-2-phenyl)benzamide 
• 105551-99-3(1R,1’R)-N-2′-hydroxy-1′-phenylethyl-1-N-dimethyl-2-phenylethylamine 
• 29686-21-3methyl-(1-methyl-2-phenyl-ethyliden)-amine 
• 136159-65-4(S)-4-benzyl-3-(3-phenylpropanoyl)oxazolidin-2-one 
• 501-52-03-Phenylpropionic acid 
• 439694-28-7(S)-2-azido-3-phenyl-propan-1-ol 
• 111525-66-7(3(2S),4S)-3-(2-azido-3-phenyl-1-oxopropyl)-4-(phenylmethyl)-2-oxazolidinone 
• 1247027-71-9C₂₁H₂₈N₂O₂*ClH 

33817-09-3Downstream Products

• 50594-12-22-[methyl-((R)-1-methyl-2-phenyl-ethyl)-amino]-ethanol 
• 2323-36-6SELEGILINE 
• 851086-85-63-((S)-1-(dimethylamino)ethyl)phenyl methyl-((R)-1-phenylpropan-2 yl)carbamate 
• 1227910-95-36-chloro-N₄-methyl-N₄-[(1R)-1-methyl-2-phenylethyl]-2,4-pyrimidinediamine 
• 851086-88-9C₂₄H₃₁N₃O₂ 
• 89362-16-3Methyl-((R)-1-methyl-2-phenyl-ethyl)-penta-2,3-dienyl-amine 
• 114351-95-0Methyl-((R)-1-methyl-2-phenyl-ethyl)-penta-2,3-dienyl-amine; compound with oxalic acid 
• 537-53-1methyl-((R)-1-methyl-2-phenyl-ethyl)-oxalamic acid hydrazide 
• 26097-55-2benzyl(methyl)[(2R)-1-phenylpropan-2-yl]amine 
• 6556-29-2(R)-2-methylamino-1-cyclohexyl-propane 

33817-09-3Relevant academic research and scientific papers

Buy Levomethamphetamine Cas 33817-09-3